Semaglutide Dosage Calculator
Enter the amount in your Semaglutide vial, the volume it is in, and the dose you want expressed in syringe units. This page computes the arithmetic of those values — concentration, the volume to draw, insulin-syringe units, and doses per vial. It is not a dosing recommendation.
- Concentration
- 5 mg/mL
- Draw volume
- 0.1 mL
- Doses per vial
- 20
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The values above are pre-filled as a worked example so the page loads with numbers to read. They are not a recommended vial size, diluent volume, or dose. Change any field to compute your own.
Semaglutide at a glance
- Also known as
- Ozempic · Wegovy · Rybelsus
- Compound class
- Incretin receptor agonist (peptide)
- Supplied as
- Lyophilized (freeze-dried) powder — dissolved in a diluent before any volume can be drawn · Ready-to-use solution supplied at a concentration stated on the label
- Vial strengths
- 2 mg lyophilized vial — commonly supplied · 5 mg lyophilized vial — commonly supplied · 10 mg lyophilized vial — commonly supplied · 15 mg lyophilized vial — commonly supplied · Ozempic 2 mg / 3 mL — FDA-approved · Ozempic 4 mg / 3 mL — FDA-approved · Ozempic 8 mg / 3 mL — FDA-approved · Wegovy 0.25 mg / 0.5 mL — FDA-approved · Wegovy 0.5 mg / 0.5 mL — FDA-approved · Wegovy 1 mg / 0.5 mL — FDA-approved · Wegovy 1.7 mg / 0.75 mL — FDA-approved · Wegovy 2.4 mg / 0.75 mL — FDA-approved
- Regulatory status
- FDA-approved prescription products containing this ingredient are marketed in the United States as ready-to-use solutions, supplied at a concentration fixed by the label rather than mixed by the user. The same ingredient is also supplied as a lyophilized powder in compounded and research presentations, which are reconstituted with a diluent before use; those presentations are not FDA-approved products, and no approved labeling defines a vial strength, a diluent, or a concentration for them.
What Semaglutide is
Semaglutide is a synthetic peptide analogue of human GLP-1 that acts as a GLP-1 receptor agonist.
FDA labeling describes it as having 94% sequence homology to human GLP-1, with a C18 fatty diacid attached to the lysine at position 26 via a hydrophilic spacer and further modifications at positions 8 and 34; its molecular weight is 4113.58 g/mol.
The FDA-approved injectable products, marketed as Ozempic and Wegovy, are supplied as ready-to-use solutions in pre-filled pens at concentrations stated on the label, and a tablet form is marketed as Rybelsus.
The same ingredient is also supplied as a lyophilized (freeze-dried) powder in compounded and research presentations; those are not FDA-approved products, and the concentration of one is set entirely by the mass in the vial and the volume of diluent added to it.
This page's calculator computes concentration, the volume to draw, and the equivalent insulin-syringe units from whatever mass and volume you enter.
Load a vial strength into the calculator
Each link re-runs the calculator above with that strength's numbers already entered.
Rows marked FDA-approved are strengths stated in approved labeling. Rows marked commonly supplied are vial sizes that compounded and research presentations are commonly supplied in; no approved labeling defines those, and what a given vial contains is only what is printed on that vial.
- 2 mg lyophilized vial — commonly supplied
- 5 mg lyophilized vial — commonly supplied
- 10 mg lyophilized vial — commonly supplied
- 15 mg lyophilized vial — commonly supplied
- Ozempic 2 mg / 3 mL — FDA-approved
- Ozempic 4 mg / 3 mL — FDA-approved
- Ozempic 8 mg / 3 mL — FDA-approved
- Wegovy 0.25 mg / 0.5 mL — FDA-approved
- Wegovy 0.5 mg / 0.5 mL — FDA-approved
- Wegovy 1 mg / 0.5 mL — FDA-approved
- Wegovy 1.7 mg / 0.75 mL — FDA-approved
- Wegovy 2.4 mg / 0.75 mL — FDA-approved
Semaglutide calculator questions
How many units is a 0.5 mg dose of Semaglutide?
With the example values on this page — 10 mg in 2 mL of bacteriostatic water — the vial works out to 5 mg/mL, so a 0.5 mg dose is 0.1 mL, which reads as 10 units on a U-100 insulin syringe. Change any field in the calculator above and the computed units change with it.
What does a 10 mg vial of Semaglutide come out to with different amounts of bacteriostatic water?
Concentration is the mass in the vial divided by the volume it is in, so changing only the volume changes every downstream number: 1 mL computes to 10 mg/mL, making a 0.5 mg dose 0.05 mL (5 units); 2 mL computes to 5 mg/mL, making a 0.5 mg dose 0.1 mL (10 units); 4 mL computes to 2.5 mg/mL, making a 0.5 mg dose 0.2 mL (20 units). Each figure is arithmetic on the two values stated, not a statement that any of those volumes is the one to use.
How many 0.5 mg doses are in a 10 mg vial of Semaglutide?
Dividing 10 mg by 0.5 mg computes to 20 full doses. Only whole doses are counted — any remainder smaller than a full dose is left out of that figure. Different vial contents or a different dose produce a different count; enter yours in the calculator above.
What concentration is 10 mg of Semaglutide in 2 mL?
10 mg in 2 mL computes to 5 mg/mL. From that concentration, the volume holding a 0.5 mg dose is 0.1 mL, or 10 units on a U-100 syringe. This page reports that division; it does not evaluate the numbers you put into it.
How much bacteriostatic water do I add to a vial of Semaglutide?
That volume is an input to this calculator, not an output of it — this page does not pick a volume for you and nothing here says which one to use. What it can tell you is what each choice computes to: 10 mg with 1 mL works out to 10 mg/mL, and the same 10 mg with 4 mL works out to 2.5 mg/mL. The mass in the vial never changes; only the concentration and the volume you would draw do.
What concentration is a Semaglutide pen or vial?
A ready-to-use solution has its concentration fixed by its labeling: the mass stated on the pen or vial divided by the volume that pen or vial holds. Its Ozempic 2 mg / 3 mL presentation computes to 0.6667 mg/mL. Entering those two numbers in the calculator above reproduces that division and reads the 2 mg draw off an insulin-syringe scale.